Aprotinin - from Bovine Lung
Aprotinin is a monomeric globular polypeptide derived from bovine lung tissue. It consists of a chain of 58 amino acids that fold into a stable, compact tertiary structure of the "small SS-rich" type, containing 3 disulfides, a twisted β-hairpin and a C-terminal α-helix.
Aprotinin inhibits several serine proteases, specifically trypsin, chymotrypsin, plasminand kallikrein. Its action on kallikrein leads to the inhibition of the formation of factor XIIa. Binding is reversible with most aprotinin-protease complexes dissociating at pH >10 or < 3.Aprotinin is freely soluble in water (>10 mg/ml) as well as low ionic strength aqueous buffers.
Product Specifications:Aprotinin(Trasylol, Trypsin inhibitor (basic), Iniprol)
Formula: C284H432N84O79S7
MW: 6511.44 g/mol
Color: White to off-white
Storage/Handling: Store at 2-8° C.
PubChem Chemical ID: 16130295
