GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!

RecombinantMurine Chemokine (C-C motif) Ligand 20 (CCL20)Liver and ActivationRegulated Chemokine (LARC)SmallInducible Cytokine Subfamily A Member 20 (SCYA20)ChemokineBeta 4 (Ckb4, Ck-β-4)Exodus,Exodus-1MacrophageInflammatory Protein 3, Alpha (MIP3α, MIP-3α)

CCL20 is a chemokine containing four conserved cysteine residues, two of which are adjacent. It is expressed in the liver as well as in lymphocytes, monocytes, and leukemia cells that have been induced by a mediator of inflammation, such as IFNG, IL1B, LPS, or PMA. It is upregulated in psoriasis because of proinflammatory mediators produced in the skin and attracts T lymphocytes to lesions. CCL20 is chemotactic mainly for lymphocytes, but also for granulocytes and immature dendritic cells and it plays a role in development of mucosal lymphoid tissue. It is a ligand for CCR6.

Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture.

Source: Escherichia coli

MW: ~8.0 kDa (70 aminoacids)

Purity: >96% by SDS-PAGEand HPLC analyses

Biological Activity: Fully biologically activewhen compared to standard. The biologically active determined by a chemotaxisbioassay using human CCR6 transfected murine BaF3 cells is in a concentrationrange of 0.1-10 ng/ml.

Storage/Handling: Store desiccated at-20°C.

MGD: 1329031

NOT FOR HUMAN USE!

Additional resources for this protein may be found at:OMIM