GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!

RecombinantMurine Chemokine (C-C motif) Ligand 17 (CCL17)Thymus andActivation Regulated Chemokine (TARC)SmallInducible Cytokine Subfamily A Member 17 (SCYA17)

CCL17 is a chemokine containing four conserved cysteine residues, two of which are adjacent. It is expressed constitutively in the thymus and lymph nodes and transiently in peripheral blood mononuclear cells that have been induced by phytogemagglutinin. It is chemotactic for T-cells and plays a role in T-cell development trafficking, and activation. CCL17 promotes atherosclerosis by restricting the maintenance of regulatory T-cells, thereby limiting their expansion. It is a ligand for CCR4, CCR8, and the erythrocyte receptor ACKR1.

Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture.

Source: Escherichia coli

MW: ~7.9 kDa (70 aminoacids)

Purity: >97% by SDS-PAGEand HPLC analyses

Biological Activity: Fully biologicallyactive when compared to standard. The biological activity determined by achemotaxis bioassay using human T-lymphocytes is in a concentration of 1.0-10ng/ml.

Storage/Handling: Store desiccated at-20°C.

MGD: 1329039

NOT FOR HUMAN USE!

Additional resources for this protein may be found at:OMIM