GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!

RecombinantHuman Chemokine (C-C motif) Ligand 15 (CCL15)HemofiltrateCC Chemokine 2 (HCC2)Small InducibleCytokine Subfamily A Member 15 (SCYA15)New CCChemokine 3 (NCC3)MacrophageInflammatory Protein 5 (MIP5, MIP-5)HumanMIP-related protein 2B (HMRB-2B)Leukotactin1 (LKN1)

CCL15 is a chemokine containing six conserved cysteine residues that form three disulfide bonds essential for biological activity. It is often proteolytically processed in to smaller chains that are more potent as chemoattractants. CCL15 is expressed in liver, intestine, colon, and lung tissue. It is chemotactic for monocytes, T-lymphocytes, and eosinophils. CCL15 causes a change in intracellular calcium levels and a release of enzymes in monocytes. It is a ligand for CCR1, as well as CCR3 to an extent. CCL15 is most similar in sequence to CCL23.

Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture.

Source: Escherichia coli

MW: ~10.2 kDa (92amino acids)

Purity: >97% by SDS-PAGEand HPLC analyses

Biological Activity: Fully biologicallyactive when compared to standard. The biological activity determined by achemotaxis bioassay using human T-lymphocytes is in a concentration of 1-10ng/ml.

Storage/Handling: Store desiccated at-20°C.

HGNC: 10613

NOT FOR HUMAN USE!

Additional resources for this protein may be found at:OMIM