GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!

RecombinantHuman Chemokine (C-C motif) Ligand 15 (CCL15)HemofiltrateCC Chemokine 2 (HCC2)SmallInducible Cytokine Subfamily A Member 15 (SCYA15)New CCChemokine 3 (NCC3)MacrophageInflammatory Protein 5 (MIP5, MIP-5)HumanMIP-related protein 2B (HMRB-2B)Leukotactin1 (LKN1)

CCL15 is a chemokine containing six conserved cysteine residues that form three disulfide bonds essential for biological activity. It is often proteolytically processed in to smaller chains that are more potent as chemoattractants. CCL15 is expressed in liver, intestine, colon, and lung tissue. It is chemotactic for monocytes, T-lymphocytes, and eosinophils. CCL15 causes a change in intracellular calcium levels and a release of enzymes in monocytes. It is a ligand for CCR1, as well as CCR3 to an extent. This recombinant protein is N-terminally truncated CCL15 (25-92) and is 100-fold more potent as a chemoattractant than the non-truncated form. CCL15 (25-92) also plays a role in mediating angiogenesis.

Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture.

Source: Escherichia coli

MW: ~7.4 kDa (68 aminoacids)

Purity: >98% by SDS-PAGEand HPLC analyses

Biological Activity: Fully biologicallyactive when compared to standard. The biological activity determined by achemotaxis bioassay using human T-lymphocytes is in a concentration of 1-10ng/ml.

Storage/Handling: Store desiccated at-20°C.

HGNC: 10613

NOT FOR HUMAN USE!

Additional resources for this protein may be found at:OMIM