GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!

RecombinantHuman Chemokine (C-C motif) Ligand 1 (CCL1)InflammatoryCytokine I-309 (I309)Small InducibleCytokine Subfamily A Member 1 (SCYA1)P500SmallInducible Secreted, Epsilon (SISE)T-CellActivation (TCA-3)

CCL1 is a chemokine containing four conserved cysteine residues, of which the first two are adjacent. It is expressed in and secreted from activated T-cells and it is chemotactic for monocytes, natural killer (NK) cells, and immature B-cells and dendritic cells. CCL1 has been shown to increase cytoplasmic calcium levels, protect T-cell lymphomas from apoptosis, and inhibit myeloid progenitors from proliferating. CCL1 is a ligand for CCR8 and is blocked by the viral CCR8 antagonist MC148R.

Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture.

Source: Escherichia coli

MW: ~8.6 kDa (74 aminoacids)

Purity: >97% by SDS-PAGEand HPLC analyses

Biological Activity: Fully biologicallyactive when compared to standard. The biological activity determined by achemotaxis bioassay using human T-lymphocytes is in a concentration of 10-100ng/ml.

Storage/Handling: Store desiccated at-20°C.

HGNC: 10609

NOT FOR HUMAN USE!

Additional resources for this protein may be found at:OMIM